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The LIS-platform, a BIM-based software platform, is being developed to monitor various aspects of buildings. This platform provides a comprehensive overview of structu...

CamSensor

A rapid biosensor for detecting Campylobacter in under 10 minutes, offering instant results via Bluetooth. This breakthrough addresses climate-related health risks and food safety, outpacing current diagnostic methods.

Rapid detection of Campylobacter
In situ detection
Ability for mass screening

- Current technologies for foodborne pathogen screening require labor-intensive sample enrichment steps, pathogen isolation and purification, and costly readout machinery.
- A point-of-care diagnostic with a potential application across the food value chain will be developed for the rapid (<3 min), in-situ detection of the most prevalent foodborne pathogen Campylobacter spp. with online registration capacity.
Addresses: Droughts, Multi-hazards

TRL4. Laboratory testing of prototype component or process
This development has been successfully tested under field and laboratory conditions in, FOODSCAN and BIOLisme projects regarding the fabrication of biosensors for the high-throughput rapid detection of specific pathogens and analytes. It is a patented method (EPO patent granted) and Publications of proof-of-concept for several clinical and food safety applications exist. Small and medium-scale clinical trials have already been performed for a clinical application (detection of SARS-CoV-2) thus the general methodology can easily be adapted for Campylobacter detection. It aims reaching TRL6 from TRL4 through the trials for its efficient exploitation in ARSINOE. This is guaranteed due to the existing core platform already in use for other applications (food safety-related ones) comprising a portable read-out device and embedded software. For the requirements and specifications of ARSINOE, it will be necessary to calibrate the system and modify/rewrite the software to comply with the project target pathogen, as well as re-access the performance characteristics.

See more information about this level and the TRL and SRL levels.

Market assessment

The market assessment of this innovation has been self-declared by the provider and has not been independently verified. For more details, please contact the innovator directly.

The system’s main components have been individually tested, and an initial integration has been completed.

Credits
CREDITS
CSO - Sofia Mavrikou
Collaborators
COLLABORATORS
No collaborators

How does it work?

Our innovation is a rapid biosensor designed to detect Campylobacter, a major cause of foodborne illness, in less than 10 minutes. This device is specifically engineered for real-time, in-situ monitoring across the food value chain, ensuring prompt detection of this pathogen. Unlike traditional methods that require extensive processing and time, our biosensor offers instant results via Bluetooth to a smartphone interface, making it highly accessible and user-friendly. The device meets WHO’s ASSURED criteria (Affordable, Sensitive, Specific, User-friendly, Rapid and robust, Equipment free, and Deliverable), addressing the critical need for quick, accurate diagnostics in urban environments where climate change exacerbates food safety risks. This breakthrough enhances public health management by providing immediate, reliable data, enabling timely intervention and reducing the incidence of Campylobacter-related illnesses.

Our technology, the Bioelectric Recognition Assay (BERA)-class bioelectric biosensors based on membrane-engineered cells, can respond to very low concentrations of an analyte (e.g., protein, pathogen) with extreme speed, specificity, and sensitivity. Cells-on-a-chip are engineered to bear target-specific antibodies on their surface. Upon binding the target, potential changes in the cell membrane produce a strong bioelectric signal. This technology has been developed and validated by the core team members through several national and EU-funded projects and is EPO-granted.

Our co-founders have been working in three distinct areas of medical/biotech diagnostics R&D and industry: (a) as university researchers with cumulative experience of 20+ years in developing pre-commercial and commercial systems, (b) as founders and executive officers of a diagnostics start-up (EMBIO Diagnostics Ltd, Nicosia, CY), and (c) as end-users/customers of routine diagnostic products in clinical practice. Therefore, their combined expertise covers the entire chain from R&D to production to customer need specification.

Cell-based consumables have a relatively short storability but we are working on the prolongation of cell viability by the use of custom-made bio-hydrogels.

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